Synthesis, analysis, in vitro characterization, and in vivo disposition of a lamivudine–dextran conjugate for selective antiviral delivery to the liver

…, HK Agarwal, A Kumar, K Parang…

Index: Reddy, K. Raja; Colby, Timothy J.; Fujitaki, James M.; Van Poelje, Paul D.; Erion, Mark D. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 375 - 381

Full Text: HTML

Citation Number: 28

Abstract

... HR-MS (ESI-TOF) (m/z): C 35 H 43 N 3 O 5 SSi calcd, 645.2693; found 686.4634 [M + K + 2H] + , 1289.3676 [2M – 1] + . 3 (–)-4-N-(4,4′-Dimethoxytrityl)-2′,3′-dideoxy-3′-thiacytidine (4 ... 1 H NMR (CD 3 OD, δ ppm): 8.53 (d, J = 7.8 Hz, 1H, H-6), 7.32–7.34 (m, 2H, aromatic ...

Related Articles:

Design, Synthesis, and Sustained??Release Property of 1, 3??Cyclic Propanyl Phosphate Ester of 18β??Glycyrrhetinic Acid

[Sun, Weizhi; Peng, Weibing; Li, Guoqiang; Jiang, Tao Chemical Biology and Drug Design, 2011 , vol. 77, # 3 p. 206 - 211]

Studies on the chemoenzymatic synthesis of (R)-and (S)-methyl 3-aryl-3-hydroxypropionates: the influence of toluene-pretreatment of lipase preparations on …

[Borowiecki, Pawel; Bretner, Maria Tetrahedron Asymmetry, 2013 , vol. 24, # 15-16 p. 925 - 936]

Phosphoramidate and phosphate prodrugs of (−)-β-d-(2R, 4R)-dioxolane-thymine: Synthesis, anti-HIV activity and stability studies

[Liang, Yuzeng; Narayanasamy, Janarthanan; Schinazi, Raymond F.; Chu, Chung K. Bioorganic and Medicinal Chemistry, 2006 , vol. 14, # 7 p. 2178 - 2189]

Design, Synthesis, and Sustained??Release Property of 1, 3??Cyclic Propanyl Phosphate Ester of 18β??Glycyrrhetinic Acid

[Sun, Weizhi; Peng, Weibing; Li, Guoqiang; Jiang, Tao Chemical Biology and Drug Design, 2011 , vol. 77, # 3 p. 206 - 211]

More Articles...