Development of an Efficient and Stereoselective Manufacturing Route to Idoxifene
KW Ace, MA Armitage, RK Bellingham…
Index: Organic Process Research and Development, , vol. 5, # 5 p. 479 - 490
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Citation Number: 9
Abstract
... Organic Process Research & Development. ... a concerted elimination of a diastereomerically enriched substrate 11 could be performed (Scheme 4). The research pursued a ... yield of ketone 13 (48%) that was isolable without chromatography (Scheme 6). This procedure was used ...
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[Ace, Karl W.; Armitage, Mark A.; Bellingham, Richard K.; Blackler, Paul D.; Ennis, David S.; Hussain, Nigel; Lathbury, David C.; Morgan, David O.; O'Connor, Noah; Oakes, Graham H.; Passey, Stephen C.; Powling, Laurence C. Organic Process Research and Development, 2001 , vol. 5, # 5 p. 479 - 490]
[Ace, Karl W.; Armitage, Mark A.; Bellingham, Richard K.; Blackler, Paul D.; Ennis, David S.; Hussain, Nigel; Lathbury, David C.; Morgan, David O.; O'Connor, Noah; Oakes, Graham H.; Passey, Stephen C.; Powling, Laurence C. Organic Process Research and Development, 2001 , vol. 5, # 5 p. 479 - 490]