Synthesis of novel 2, 7-disubstituted-3-amino-9-trifluoromethyl-4-oxo-4H-pyrido-[3', 2': 4, 5]-furo-[3, 2-d]-(1, 3)-pyrimidines

B Narsaiah, A Sivaprasad…

Index: Narsaiah, B.; Sivaprasad, A.; Venkataratnam, R. V. Journal of Fluorine Chemistry, 1994 , vol. 69, # 2 p. 139 - 144

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Citation Number: 7

Abstract

Abstract Synthesis of novel 2, 7-disubstituted-3-amino-9-trifluoromethyl-4-oxo-4H-pyrido-[3', 2': 4, 5]-furo-[3, 2-d]-(1, 3)-pyrimidines (5) from 3-cyano-4-trifluoromethyl-6-substituted 2 (1H)- pyridones (1) via a series of new intermediates such as 2-O-ethylacetoxy-3-cyano-4- trifluoromethyl-6-substituted pyridines (2), 2-carbethoxy-3-amino-4-trifluoromethyl-6- substituted furo-[2, 3-b]-pyridines (3) and 2-carbohydrazide-3-amino-4-trifluoromethyl-6- ...