Helvetica Chimica Acta

Ring Opening of 2??(Benzylamino)??2H??1, 4??benzoxazin??3 (4H)??ones and 2??Bromo??2H??1, 4??benzoxazin??3 (4H)??ones

J Ilaš, D Kikelj

Index: Ilas, Janez; Kikelj, Danijel Helvetica Chimica Acta, 2008 , vol. 91, # 4 p. 654 - 664

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Abstract

Abstract Substituted 2-(benzylamino)-2H-1, 4-benzoxazin-3 (4H)-ones are unstable under alkaline and acidic conditions, undergoing opening of the benzoxazinone ring. 2-Bromo-2H- 1, 4-benzoxazin-3 (4H)-ones show similar degradation under alkaline conditions, while replacement of Br at C (2) to give 2-hydroxy-2H-1, 4-benzoxazin-3 (4H)-ones was observed only under mild alkaline conditions. Mechanisms of ring opening and degradation to 2- ...

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Ring Opening of 2??(Benzylamino)??2H??1, 4??benzoxazin??3 (4H)??ones and 2??Bromo??2H??1, 4??benzoxazin??3 (4H)??ones

Abstract

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