Fragment-based discovery of bromodomain inhibitors part 2: optimization of phenylisoxazole sulfonamides

P Bamborough, H Diallo, JD Goodacre…

Index: Journal of Medicinal Chemistry, , vol. 55, # 2 p. 587 - 596

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Citation Number: 106

Abstract

... Journal of Medicinal Chemistry. ... Computational & Structural Chemistry, Molecular Discovery Research, GlaxoSmithKline R&D, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire SG1 2NY, UK. ...