Australian Journal of Chemistry

Synthesis of Casein-Related Peptides and Phosphopeptides. V. The Efficient Global'Phosphite-Triester'Phosphorylation of Protected Serine Derivatives and Peptides …

JW Perich, RB Johns

Index: Perich, John W.; Johns, R. B. Australian Journal of Chemistry, 1990 , vol. 43, p. 1623 - 1632

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Citation Number: 25

Abstract

Abstract Both dibenzyl N, N-diethylphosphoramidite and di-t-butyl N, N- diethylphosphoramidite are shown to be suitable reagents for the efficient 1H-tetrazole- catalysed'phosphite-triester'phosphorylation of the protected serine derivative Boc-Ser-OCH 2 C 6 H 4 NO 2-p. Both these reagents were also used for the phosphorylation of the protected serine derivative Boc-Glu (OBu t)-Ser-Leu-OBu t, and subsequent ...

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