Acrylate as an Efficient Dimethylamine Trap for the Practical Synthesis of 1-tert-Butyl-4-piperidone via Transamination

JS Amato, JYL Chung, RJ Cvetovich…

Index: Tortolani, David R.; Poss, Michael A. Organic Letters, 1999 , vol. 1, # 8 p. 1261 - 1262

Full Text: HTML

Citation Number: 10

Abstract

... Furthermore, hindered amines tended to produce bis-amine Michael adducts. figure ... Evaporation of the organic extracts afforded essentially pure 1 in 87% assay yield. ... Chim. Acta 1966, 49, 690−695. [CrossRef], [CAS] Synthesis of 4-chloropiperidines. Fankhauser, R.; Grob, CA ...

Related Articles:

… observations relating to the use of 1-aryl-4-alkoxypiperidin-4-yl groups for the protection of the 2′-hydroxy functions in the chemical synthesis of oligoribonucleotides

[Lloyd, Wayne; Reese, Colin B.; Song, Quanlai; Vandersteen, Anthony M.; Visintin, Cristina; Zhang, Pei-Zhou Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 2 p. 165 - 176]

More Articles...