The A-CD analogue of 16β, 17α-estriol is a potent and highly selective estrogen receptor β agonist

C Sauvée, A Schäfer, H Sundén, JN Ma…

Index: MedChemComm, , vol. 4, # 11 p. 1439 - 1442

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Citation Number: 2

Abstract

... 11. Fig. ... For details see ESI.†. Scheme 3 Reagents and conditions for the A-CD 16,17-epiestriol analogue synthesis. (m) Isopropenyl acetate, H 2 SO 4 conc., 70 °C, 16 h; (n) m-CPBA, toluene, rt, 20 h; (o) LiAlH 4 , THF, rt, 2 h; (p) NH 4 OAc, MeOH : H 2 O 4 : 1, rt, 2 h. ...

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