Pyridazines. XXV. Formation of 2??benzoyl??2, 5??dihydro??3??pyridazinecarbonitrile derivatives in the reissert reaction of pyridazines

W Dostal, G Heinisch

Index: Dostal, Wolfgang; Heinisch, Gottfried Journal of Heterocyclic Chemistry, 1985 , vol. 22, p. 1543 - 1546

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Citation Number: 6

Abstract

Abstract Pyridazines 1a, b on treatment with potassium cyanide/benzoyl chloride in a mixed solvent system gave 2-benzoyl-2, 5-dihydro-3-pyridazinecarbonitriles 3a, b together with products resulting from attack of one mole of cyanide ion and three moles of benzoyl chloride (5a, b). The structures of these novel compounds are proved. A plausible reaction mechanism is proposed, involving rearrangement of initially formed 2a, b into 3a, b. ...