Tetrahedron Letters

The synthesis of trospectomycin (6′-n-propylspectinomycin, U-63,366 f) from spectinomycin

DR White, GA Cain

Index: White, David R.; Cain, Gary A. Tetrahedron Letters, 1989 , vol. 30, # 12 p. 1469 - 1472

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Citation Number: 5

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Spectinomycin (1) can, for the first time, be activated in the sensitive sugar ring and be carried on to trospectomycin, 6′-propylspectinomycin (2), in a simplified process. ... The sensitive sugar ring of spectinomycin can be activated, as an enolacetate (8), to obtain a key enone (5b). ...