Synthesis and Antimycobacterial Activity of Novel Thiadiazolylhydrazones of 1??Substituted Indole??3??carboxaldehydes

K Haj Mohammad Ebrahim Tehrani…

Index: Chemical Biology and Drug Design, , vol. 83, # 2 p. 224 - 236

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Abstract

... Chemical Biology & Drug Design, 83: 224–236. doi: 10.1111/cbdd.12230. ... Studies on thiacetazone suggest that the drug is metabolized by EthA, the mycobacterial enzyme that is considered as the activator of thiocarbonyl antimycobacterial drugs [5-7]. Dover et al. ... Chemistry. ...

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