Preparation of ribosyl derivatives of 1, 2, 4-triazol-3 (2H)-one and 5-methyl-1, 2, 4-triazol-3 (2H)-one

H Hřebabecký, J Beránek

Index: Hrebabecky, Hubert; Beranek, Jiri Collection of Czechoslovak Chemical Communications, 1985 , vol. 50, # 2 p. 779 - 788

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Citation Number: 6

Abstract

Abstract Reaction of the silylated triazolone I with 2, 3, 5-tri-O-benzoyl-D-ribofuranosyl bromide afforded a mixture of the 4-ribosyltriazolone IXa and 2, 3-diribosyltriazolone Xa. Under the same conditions the silylated 5-methyltriazolone II gives the 4-ribosyl derivative XIa and 2-ribosyl derivative XIIa. The 4-phenyl and 4-ribosyltriazoles VII, VIII, IXa and XIa were prepared by an alternative synthesis: cyclisation of l-ethoxymethylene-, l-(l- ...

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