Discovery of novel antileishmanial agents in an attempt to synthesize pentamidine− aplysinopsin hybrid molecule

S Porwal, SS Chauhan, PMS Chauhan…

Index: Journal of Medicinal Chemistry, , vol. 52, # 19 p. 5793 - 5802

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Citation Number: 51

Abstract

... Journal of Medicinal ... Division of Medicinal & Process ... Chemistry To synthesize compound 25 and its analogues, we adopted the route depicted in Scheme 1. Direct synthesis of aplysinposin and its subsequent coupling with the pentamidine fragment was not feasible because of ...