Regioselective acylation of 1, 6-anhydro-β-D-manno and galactopyranose catalysed by lipases

N Junot, JC Meslin, C Rabiller

Index: Junot, N.; Meslin, J.C.; Rabiller, C. Tetrahedron: Asymmetry, 1995 , vol. 6, # 6 p. 1387 - 1392

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Citation Number: 11

Abstract

Pseudomonas fluorescens lipase (Amano) was found to be highly regioselective in the transesterification of 1, 6-anhydro-β-D-manno and galactopyranoses (mannosane and galactosane respectively) using vinyl acetate as an acyl donor. As in the case of 1, 6- anhydro-β-D-glucopyranose (glucosane), the 4-OH axial group of mannosane is preferred, while the titled lipase catalysed the regioselective transesterification at the 2-axial OH of ...