Nucleosides, Nucleotides and Nucleic Acids

Stacking Conformation of 9-[ω-(Thymin-1-yl) alkyl] adenine in Aqueous Solution

T Itahara

Index: Itahara, Toshio Nucleosides, Nucleotides and Nucleic Acids, 2003 , vol. 22, # 3 p. 309 - 317

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Abstract

Abstract An intramolecular stacking between adenine and thymine rings of 9-[ω-(thymin-1-yl) alkyl] adenine was investigated by means of NMR and UV spectroscopy. The stacking conformation was presumed on the basis of the temperature dependence on the chemical shifts of the adenine and thymine ring protons in the buffer solution at pD 7.0.

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