4-Aminoarylguanidine and 4-aminobenzamidine derivatives as potent and selective urokinase-type plasminogen activator inhibitors

…, C Luong, M Sendzik, N Squires, RL Mackman

Index: Spencer, Jeffrey R; McGee, Danny; Allen, Darin; Katz, Bradley A; Luong, Christine; Sendzik, Martin; Squires, Neil; Mackman, Richard L Bioorganic and Medicinal Chemistry Letters, 2002 , vol. 12, # 15 p. 2023 - 2026

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Citation Number: 21

Abstract

Download PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... The structure-based design of potent and selective urokinase-type plasminogen activator (uPA) inhibitors with 4-aminoarylamidine or 4-aminoarylguanidine S1 binding groups, is described. ... The structure-based design of potent and selective inhibitors of uPA with 4-aminoarylamidine ...