Substituent effect investigation of 3??(2, 4??dichlorophenyl)??1??(4′??X??phenyl)??2??propen??1??one. Part 1. Correlation analysis of 13C NMR chemical shifts

A Perjessy, HK Al??Amood, GF Fadhil…

Index: Perjessy; Al-Amood; Fadhil; Pronayova Journal of Physical Organic Chemistry, 2011 , vol. 24, # 2 p. 140 - 146

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Citation Number: 2

Abstract

Abstract A series of substituted chlorinated chalcones namely, 3-(2, 4-dichlorophenyl)-1-(4′- X-phenyl)-2-propen-1-one, have been synthesized, X being H, NH 2, OMe, Me, F, Cl, CO 2 Et, CN, and NO 2. Dual substituent parameter (DSP) models of 13 C NMR chemical shift (CS) have revealed that π-polarization concept could be utilized to explain the reverse field effect at CO, the enhanced substituent field effect at CO, C-2, and C-5, and the decreased ...