Secondary amines from trifluoroacetamides

AP King, CG Krespan

Index: King,A.P.; Krespan,C.G. Journal of Organic Chemistry, 1974 , vol. 39, p. 1315 - 1316

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Citation Number: 30

Abstract

2 acetyl group to participate in coordination to alkali metal ion, so that no template effect5 is available to assist ring closure. In any event, reaction of bis (trifluor0acetamide) 2 as the disodium salt with the ditosylate of triethylene glycol in dimethylformamide gave, after basic hydrolysis, 3% of purified diamine 1, whereas the same reaction with 1, 8-dichloro-3, 6- dioxaoctane in place of ditosylate gave none of diamine 1. In contrast, the synthesis ...