Synthesis and biological activity of 4-substituted 1, 2-naphthoquinones, 1, 2-naphthalenediols, and their derivatives

…, IK Arsenichev, IS Nikolaeva, LA Golovanova…

Index: Grinev, A. N.; Arsenichev, I. K.; Nikolaeva, I. S.; Golovanova, L. A.; Pushkina, T. V.; et al. Pharmaceutical Chemistry Journal, 1985 , vol. 19, # 6 p. 411 - 417 Khimiko-Farmatsevticheskii Zhurnal, 1985 , vol. 19, # 6 p. 699 - 705

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Abstract

0091-150X/85/1906-0411509.50 9 1986 Plenum Publishing Corporation 411 f). During oxidation, compounds lla-c converted into the corresponding derivatives of i, 2- naphthoquinone (llla-c). Diols lie, f underwent polymerization during oxidation. Reduction of 1, 2-naphthoquinones llla-c by sodium hydrosulfite gave the 1, 2-naphthalenediols ll-ac again. When sodium methylate in MeOH was used in the condensation of quinone Ic with ...