Tetrahedron

Cationic dirhodium carboxylate-catalyzed synthesis of dihydropyrimidones from propargyl ureas

M Yang, SJ Odelberg, Z Tong, DY Li, RE Looper

Index: Yang, Miao; Odelberg, Shannon J.; Tong, Zongzhong; Li, Dean Y.; Looper, Ryan E. Tetrahedron, 2013 , vol. 69, # 27-28 p. 5744 - 5750

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Citation Number: 10

Abstract

Cationic Rh (II) complexes are able to catalyze the regioselective hydroamination of propargyl ureas in a 6-endo fashion. This transformation permits access to interesting substitution patterns of dihydropyrimidines, which have found use as nucleotide exchange factor inhibitors.