General method for the synthesis of 5-arylpyrrole-2-carboxylic acids
…, A Rubio, J Valenciano, JLG Navio, J Alvarez-Builla…
Index: Ezquerra, Jesus; Pedregal, Concepcion; Rubio, Almudena; Valenciano, Jesus; Garcia Navio, Jose Luis; Alvarez-Builla, Julio; Vaquero, Juan Jose Tetrahedron Letters, 1993 , vol. 34, # 39 p. 6317 - 6320
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Citation Number: 32
Abstract
Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... 5-Arylpyrrole-2-carboxylic acids are prepared by DDQ oxidative aromatization of the corresponding ethyl 2-aryl-Δ 1 -pyrroline-5-carboxylate followed by basic hydrolysis. ... Ethyl N-BOC pyroglutamate 1 undergoes ring opening with aryl Grignard reagents togive after deprotection ethyl ...