Formation of a neutral covalent adduct in the nucleophilic aromatic substitution reaction involving a carbon leaving group

P Mencarelli, F Stegel

Index: Mencarelli, Paolo; Stegel, Franco Journal of Organic Chemistry, 1985 , vol. 50, # 25 p. 5415 - 5417

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Citation Number: 7

Abstract

Figure 2. As figure 1:(a) after 80 min;(b) after 140 min;(c) after 200 min;(d) after 260 min;(e) after 320 min;(0 after 24 h. exchanging compounds). With time, though, the intensities of d the above sign& decrease, and correspondingly the intensity of the signals of 4- methoxyquinazoline (2) increases. Compound 2 (Figure 3d) is the only final product, and is not further affected by MeO-ion under these conditions. Of course in CD, OD CDC1, ...