Lipidic peptides, I. Synthesis, resolution and structural elucidation of lipidic amino acids and their homo??and hetero??oligomers

…, M Charalambous, M Christodoulou…

Index: Gibbons, William A.; Hughes, Richard A.; Charalambous, Mario; Christodoulou, Marika; Szeto, Alice; et al. Liebigs Annalen der Chemie, 1990 , # 12 p. 1175 - 1183

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Citation Number: 131

Abstract

Abstract The α-amino acids with long alkyl side chains, the so-called lipidic amino acids 1a– e, and their homo-oligomers, the lipidic peptides 1p–aj, represent a class of compounds which combine the structural properties of peptides and proteins with the characteristics of lipids and membranes. The amino acids were synthesised from the appropriate alkyl bromide and diethyl acetamidomalonate. Resolution was made chemically, by forming ...

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