Fundamental structure–Activity relationships associated with a new structural class of respiratory syncytial virus inhibitor

…, KF Kadow, C Cianci, M Krystal, NA Meanwell

Index: Yu, Kuo-Long; Zhang, Yi; Civiello, Rita L.; Kadow, Kathleen F.; Cianci, Christopher; Krystal, Mark; Meanwell, Nicholas A. Bioorganic and Medicinal Chemistry Letters, 2003 , vol. 13, # 13 p. 2141 - 2144

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Citation Number: 55

Abstract

Structure–activity relationships surrounding the dialkylamino side chain of a series of benzotriazole-derived inhibitors of respiratory syncytial virus fusion based on the screening lead 1a were examined. The results indicate that the topology of the side chain is ...