Reactions of the derivatives of 5-bromopyrimidine nucleosides with sodium azide

T Sasaki, K Minamoto, M Kino…

Index: Sasaki,T. et al. Journal of Organic Chemistry, 1976 , vol. 41, p. 1100 - 1104

Full Text: HTML

Citation Number: 12

Abstract

To exploit azide chemistry in the nucleoside field, protected 5-bromopyrimidine nucleosides were synthesized as substrates for the reaction of azide ion. These include 2', 3'-0- isopropylidene-5'-O-benzoyl- and-5'-O-tosyl-5-bromouridine (2a and 2b), 2', 3'-0-anisylidene- 5'-O-benzoyl-5-bromouridine (2c), and 2', 3'-0-isopropylidene-5'-0-mesyl-5-bromocytidine (1 1). 2a, b with sodium azide yielded the same compound, 9, 5'-cyclo-3-(2', 3'-O-isopro- ...

Related Articles:

Synthesis and Anti-Hcv Activity of N 9, 5′-Cyclo-3-(β-D-Ribofuranosyl)-8-Azapurin-2-One Derivatives

[Hassan, Abdalla E. A.; Wang, Peiyuan; McBrayer, Tamara; Tharnish, Philip; Stuyver, Lieven; Otto, Michael J.; Watanabe, Kyoichi A.; Schinazi, Raymond F. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 10-12 p. 1531 - 1542]

Synthesis and Anti-Hcv Activity of N 9, 5′-Cyclo-3-(β-D-Ribofuranosyl)-8-Azapurin-2-One Derivatives

[Hassan, Abdalla E. A.; Wang, Peiyuan; McBrayer, Tamara; Tharnish, Philip; Stuyver, Lieven; Otto, Michael J.; Watanabe, Kyoichi A.; Schinazi, Raymond F. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 10-12 p. 1531 - 1542]

Synthesis and Anti-Hcv Activity of N 9, 5′-Cyclo-3-(β-D-Ribofuranosyl)-8-Azapurin-2-One Derivatives

[Hassan, Abdalla E. A.; Wang, Peiyuan; McBrayer, Tamara R.; Tharnish, Phillip M.; Stuyver, Lieven J.; Schinazi, Raymond F.; Otto, Michael J.; Watanabe, Kyoichi A. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 961 - 964]

Synthesis and Anti-Hcv Activity of N 9, 5′-Cyclo-3-(β-D-Ribofuranosyl)-8-Azapurin-2-One Derivatives

[Hassan, Abdalla E. A.; Wang, Peiyuan; McBrayer, Tamara R.; Tharnish, Phillip M.; Stuyver, Lieven J.; Schinazi, Raymond F.; Otto, Michael J.; Watanabe, Kyoichi A. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 5-7 p. 961 - 964]

Synthesis and Anti-Hcv Activity of N 9, 5′-Cyclo-3-(β-D-Ribofuranosyl)-8-Azapurin-2-One Derivatives

[Hassan, Abdalla E. A.; Wang, Peiyuan; McBrayer, Tamara; Tharnish, Philip; Stuyver, Lieven; Otto, Michael J.; Watanabe, Kyoichi A.; Schinazi, Raymond F. Nucleosides, Nucleotides and Nucleic Acids, 2005 , vol. 24, # 10-12 p. 1531 - 1542]

More Articles...