Highly a nti-Selective Catalytic Aldol Reactions of Amides with Aldehydes
S Saito, S Kobayashi
Index: Saito, Susumu; Kobayashi, Shu Journal of the American Chemical Society, 2006 , vol. 128, # 27 p. 8704 - 8705
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Citation Number: 97
Abstract
Barium phenoxide-catalyzed, highly anti-selective direct-type aldol reactions of amides with aldehydes have been developed. In the presence of a slight excess amount of an amide, the desired reactions proceeded smoothly under mild conditions, and a wide range of aromatic, heterocyclic, α, β-unsaturated aldehydes were applicable to afford the desired adducts in high yields with high anti-selectivities. A catalytic, enantioselective reaction of an amide ...
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