Reactivity of benzohydrazide derivatives towards acetylation reaction. Experimental and theoretical studies

…, ME Aliaga, JG Santos, EA Castro, R Contreras

Index: Campodonico, Paola R.; Aliaga, Margarita E.; Santos, Jose G.; Castro, Enrique A.; Contreras, Renato Chemical Physics Letters, 2010 , vol. 488, # 1-3 p. 86 - 89

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Citation Number: 10

Abstract

We herein report an experimental and theoretical study on the acetylation reaction of benzohydrazide derivatives towards p-nitrophenyl acetate (NPA). The kinetic data are consistent with a stepwise mechanism with the nucleophilic attack as the rate determining step. From the theoretical analysis it is found that benzohydrazide derivatives establish intramolecular proton rearrangement. The enol form appears as the active species for ...

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