Synthesis of triazole-functionalized 2-DOS analogues and their evaluation as A-site binders

P Anastasopoulou, G Kythreoti, T Cosmidis…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 24, # 4 p. 1122 - 1126

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Citation Number: 3

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... The desired triazole functionality was firstly introduced at position 3 (Scheme 2 numbering) of advanced intermediate 9 by its reaction with propargyl alcohol under standard 'click chemistry' conditions, 28 furnishing 10. ...