Journal of the American Chemical Society

Benzimidazole Syntheses by Oxidative Cyclization with Peroxytrifluoroacetic Acid

MD Nair, R Adams

Index: Nair,M.D.; Adams,R. Journal of the American Chemical Society, 1961 , vol. 83, p. 3518 - 3521

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Citation Number: 32

Abstract

Peroxytrifluoroacetic acid has been shown to be a useful reagent for the oxidation of aromatic amines to nitro compounds, olefins to epoxides, ketones to esters, 3 and N-nitroso compounds to N-nitro compounds. This reagent represents a distinct improvement over Car0 acid or peracetic acid for similar oxidations; for example, oxidation of aniline with Car0 acid is reported to give 1lyO of nitrobenzene in contrast to yields up to 89% realized by ...