Revisiting secondary structures in NCA polymerization: Influences on the analysis of protected polylysines

D Huesmann, A Birke, K Klinker, S Türk…

Index: Huesmann, David; Birke, Alexander; Klinker, Kristina; Tuerk, Stephan; Raeder, Hans Joachim; Barz, Matthias Macromolecules, 2014 , vol. 47, # 3 p. 928 - 936

Full Text: HTML

Citation Number: 25

Abstract

Two series (degree of polymerization: 20–200) of polylysines with Z and TFA protecting groups were synthesized, and their behavior in a range of analytical methods was investigated. Gel permeation chromatography of the smaller polypeptides reveals a bimodal distribution, which is lost in larger polymers. With the help of GPC, NMR, circular dichroism (CD), and MALDI-TOF, it was demonstrated that the bimodal distribution is not due to ...

Related Articles:

Synthesis of semisynthetic dipeptides using N-carboxyanhydrides and chiral induction on Raney nickel. A method practical for large scale

[Blacklock; Shuman; Butcher; Shearin Jr.; Budavari; Grenda Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 836 - 844]

N-trifluoroacyl lysine derivatives in the synthesis of L-Lysyl-L-glutamic acid

[Cherevin; Gulevich; Popova; Zubreichuk; Knizhnikov Russian Journal of Organic Chemistry, 2007 , vol. 43, # 10 p. 1427 - 1431]

The behavior of poly (amino acids) containing l??cysteine and their block copolymers with poly (ethylene glycol) on gold surfaces

[Obeid, Rodolphe; Armstrong, Tracy; Peng, Xiaoju; Busse, Karsten; Kressler, Joerg; Scholz, Carmen Journal of Polymer Science, Part A: Polymer Chemistry, 2014 , vol. 52, # 2 p. 248 - 257]

Synthesis of semisynthetic dipeptides using N-carboxyanhydrides and chiral induction on Raney nickel. A method practical for large scale

[Blacklock; Shuman; Butcher; Shearin Jr.; Budavari; Grenda Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 836 - 844]

Synthesis of semisynthetic dipeptides using N-carboxyanhydrides and chiral induction on Raney nickel. A method practical for large scale

[Blacklock; Shuman; Butcher; Shearin Jr.; Budavari; Grenda Journal of Organic Chemistry, 1988 , vol. 53, # 4 p. 836 - 844]

More Articles...