Total Synthesis, Absolute Configuration, and Biological Activity of Xyloallenoide A

SY Wang, ZL Xu, H Wang, CR Li, LW Fu…

Index: Wang, San-Yong; Xu, Zhong-Liang; Wang, Hui; Li, Chun-Rong; Fu, Li-Wu; Pang, Ji-Yan; Li, Jing; She, Zhi-Gang; Lin, Yong-Cheng Helvetica Chimica Acta, 2012 , vol. 95, # 6 p. 973 - 982

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Citation Number: 2

Abstract

Abstract The novel natural product xyloallenoide A, isolated from the marine mangrove endophytic fungus from the South China Sea, and its diastereoisomer xyloallenoide A1, which contain N-methyl-substituted amino acids, were synthesized. The absolute configurations of the amino acid units of xyloallenoide A were finally confirmed to be L-Lys, Me-D-Val, and Me-L-Ala. This report represents a practical and attractive alternative for ...