Tetrahedron letters

Stereoselective synthesis of trans-olefins by the copper-mediated SN 2′ reaction of vinyl oxazines with Grignard reagents. Asymmetric synthesis of d-threo- …

OV Singh, H Han

Index: Knapp; Patel Tetrahedron Letters, 1982 , vol. 23, # 35 p. 3539 - 3542

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Citation Number: 11

Abstract

... Tetrahedron Letters. Volume 48, Issue 13, 26 March 2007, Pages 2345–2348. ... In this Letter, we report the novel S N 2′ reaction of vinyl oxazines I with Grignard reagents in the presence of CuCN, which proceeds with high trans selectivity for double bond formation. ...