Synthesis

Comparative lipase-catalyzed hydrolysis of ethylene glycol derived esters. The 2-methoxyethyl ester as a protective group in peptide and glycopeptide synthesis

M Gewehr, H Kunz

Index: Gewehr, Markus; Kunz, Horst Synthesis, 1997 , # 12 p. 1499 - 1510

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Citation Number: 15

Abstract

Comparison of the lipase-catalyzed cleavage of polar esters derived from ethylene glycol proved 2-methoxyethyl (ME) esters most favorable protecting groups for the carboxylic function of peptides and glycopeptides. They combine high substrate acceptance and high

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