Synthesis of 1, 3-dialkyl-5-(hetaryl-1-yl)-1, 3-dihydrobenzimidazol-2-ones

…, OY Pankina, AI Bondarenko, YS Borodkin…

Index: Smolyar; Pankina, O.Yu.; Bondarenko; Borodkin, Ya.S.; Khizhan Russian Journal of Organic Chemistry, 2011 , vol. 47, # 8 p. 1190 - 1193

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Abstract

Abstract Reactions of 5-amino-1, 3-dialkyl-1, 3-dihydrobenzimidazol-2-ones with 2, 5- dimethoxytetrahydrofuran and 2, 6-dimethyl-γ-pyranone led to the formation of 1, 3-dialkyl-1, 3-dihydro-5-(pyrrol-1-andл) benzimidazol-2-ones and 1-(1, 3-dialkyl-2-oxo-1, 3- dihydrobenzimidazol-5-yl)-2, 6-dimethylpyridin-4-ones.

Quinazoline-based multi-tyrosine kinase inhibitors: synthesis, modeling, antitumor and antiangiogenic properties

[Conconi, Maria Teresa; Marzaro, Giovanni; Urbani, Luca; Zanusso, Ilenia; Di Liddo, Rosa; Castagliuolo, Ignazio; Brun, Paola; Tonus, Francesca; Ferrarese, Alessandro; Guiotto, Adriano; Chilin, Adriana European Journal of Medicinal Chemistry, 2013 , vol. 67, p. 373 - 383]

Quinazoline-based multi-tyrosine kinase inhibitors: synthesis, modeling, antitumor and antiangiogenic properties

Synthesis of 1, 3-dialkyl-5-(hetaryl-1-yl)-1, 3-dihydrobenzimidazol-2-ones

Abstract

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