The synthesis of biphenomycin B

…, V Leitenberger, A Lieberknecht, H Griesser

Index: Schmidt, Ulrich; Meyer, Regina; Leitenberger, Volker; Lieberknecht, Albrecht; Griesser, Helmut Journal of the Chemical Society, Chemical Communications, 1991 , # 5 p. 275 - 277

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Citation Number: 20

Abstract

Biphenomycins A la and B lb are cyclic tripeptides exhibiting high antibiotic activities against Gram-positive, (3-lactam- resistant bacteria which have been isolated from culture filtrates of Streptomyces griseorubiginosus NO. 43708.1 These cyclopeptides, together with those of the vancomycin group, are unique in that they contain a biphenyl structural moiety. The compounds inhibit cell wall synthesis but, unlike the antibiotics of the vancomycin group, they ...

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