Chemical Communications

N-aroyloxy-2-thiopyridones as efficient oxygen-radical generators: novel time-controlled DNA photocleaving reagents

EA Theodorakis, KM Wilcoxen

Index: Theodorakis, Emmanuel A.; Wilcoxen, Keith M. Chemical Communications, 1996 , # 16 p. 1927 - 1928

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Citation Number: 10

Abstract

N-Aroyloxy-2-thiopyridones as efficient oxygen-radical generators: novel time-controlled DNA photocleaving reagents ... Emmanuel A. Theodorakis* and Keith M. Wilcoxen Department of Chemistry and Biochemistry, University of California, 92093-0358 ... N-Aroyloxy-2-thiopyridones efficiently cleave DNA upon visible light illumination via the formation of aroyloxyl radicals. ... Cell damaging effects by oxygen radicals are well recognized in several biological ...

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