Regiospecific synthesis of arylfurans employing a nickel (II)-phosphine complex as a catalyst in the homolytic cross-coupling of Grignard reagents to halofurans

LN Pridgen, SS Jones

Index: Pridgen, Lendon N.; Jones, Stella S. Journal of Organic Chemistry, 1982 , vol. 47, # 8 p. 1590 - 1592

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Citation Number: 36

Abstract

above produce 3-arylfurans which are also only accessible through lengthy and inefficient routes. 12 We have previously shown how transition metal-phosphine complexes may be used to catalyze cross-coupling of Grignard reagents to haloheterocycles to form the corresponding aryl or arylalkyl heter~ cycles.'~ J~ This Grignard cross-coupling reaction, surprisingly, has not been extended to include furans, which are important organic ...