Ruthenium-catalyzed amidation of nitriles with amines. A novel, facile route to amides and polyamides

S Murahashi, T Naota, E Saito

Index: Murahashi, Shun-Ichi; Naota, Takeshi; Saito, Eiichiro Journal of the American Chemical Society, 1986 , vol. 108, # 24 p. 7846 - 7847

Full Text: HTML

Citation Number: 135

Abstract

In the field of amide synthesis, a problem of continuing interest is the development of a general method for the conversion of amines to amides under neutral c0nditions. l Toward this end we have devised a new type of highly efficient method, which is applicable for synthesis of various amides and polyamides. Ruthenium-catalyzed condensation of nitriles with amines in the presence of 2 equiv of water provides the corresponding amides along ...

Related Articles:

Facile reduction of pyridines with nickel-aluminum alloy

[Lunn, George; Sansone, Eric B. Journal of Organic Chemistry, 1986 , vol. 51, # 4 p. 513 - 517]

Free and supported phosphorus ylides as strong neutral Brønsted bases

[Goumri-Magnet; Guerret; Gornitzka; Cazaux; Bigg; Palacios; Bertrand Journal of Organic Chemistry, 1999 , vol. 64, # 10 p. 3741 - 3744]

A novel and efficient oxidation of 1, 2-amino alcohols to dialkylamides

[Garcia-Valverde, Maria; Pedrosa, Rafael; Vicente, Martina Synlett, 2002 , # 12 p. 2092 - 2094]

Ti (oi-pr) 4 mediated lactamizations

[Mader, Mary; Helquist, Paul Tetrahedron Letters, 1988 , vol. 29, # 25 p. 3049 - 3052]

Hypervalent iodine oxidation of amines using iodosobenzene: Synthesis of nitriles, ketones and lactams

[Moriarty, Robert M.; Vaid, Radhe K.; Duncan, Michael P.; Ochiai, Masahito; Inenaga, Minako; Nagao, Yoshimitsu Tetrahedron Letters, 1988 , vol. 29, # 52 p. 6913 - 6916]

More Articles...