Transition Metal-Catalyzed Intramolecular Cyclization of 1, 5-and 1, 6-Dienes via Direct Cleavage and Addition of the Carbon-Hydrogen Bond.

…, F Kakiuchi, A Yamada, N Chatani, S Murai

Index: Fujii, Naoaki; Kakiuchi, Fumitoshi; Yamada, Airi; Chatani, Naoto; Murai, Shinji Bulletin of the Chemical Society of Japan, 1998 , vol. 71, # 1 p. 285 - 298

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Citation Number: 72

Abstract

Ruthenium-and rhodium-catalyzed intramolecular C–H/olefin coupling reactions of 1-(2- pyridyl)-, 1-(2-imidazolyl)-, and 1-(2-oxazolyl)-1, 5-dienes proceeded in a regiospecific manner to give 5-membered ring products. Their 1, 6-diene analogues are also applicable to the cyclization reaction to give the corresponding 5-and 6-membered carbocycles. For the cyclization of the pyridine derivatives,[RhCl (PPh 3) 3] showed the highest catalytic activity ...