S-Alk (en) ylmercaptocysteine: Chemical synthesis, biological activities, and redox-related mechanism

G Zhang, KL Parkin

Index: Zhang, Guodong; Parkin, Kirk L. Journal of Agricultural and Food Chemistry, 2013 , vol. 61, # 8 p. 1896 - 1903

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Citation Number: 5

Abstract

S-Alk (en) ylmercaptocysteine (CySSR, R= methyl, ethyl, propyl, 1-propenyl, and allyl), which are the putative metabolites of Allium thiosulfinates, were chemically synthesized. CySSR, but not the corresponding monosulfide species S-alk (en) yl cysteine (CySR), were able to induce quinone reductase (QR, a representative phase II enzyme) in Hepa 1c1c7 cells and inhibit nitric oxide (NO, an inflammatory biomarker) formation in ...