Angewandte Chemie International Edition

An Engineered Linker Capable of Promoting On??Resin Reactions for Microwave??Assisted Solid??Phase Organic Synthesis

LP Sun, WM Dai

Index: Sun, Li-Ping; Dai, Wei-Min Angewandte Chemie - International Edition, 2006 , vol. 45, # 43 p. 7255 - 7258

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Citation Number: 26

Abstract

Solid-phase organic synthesis (SPOS)[1] has emerged as one of the key tools in combinatorial chemistry [2] for generating libraries of small organic molecules. In order to transfer the versatile reaction types established in solution to solid-phase synthesis, numerous classes of linkers [1–3] have been developed, including traceless and multifunctional linkers.[4] The latter enable the generation of diversity in the end products ...