Synthesis and antitumor activity of quaternary ellipticine glycosides, a series of novel and highly active antitumor agents

T Honda, M Kato, M Inoue, T Shimamoto…

Index: Honda, Tadashi; Kato, Mika; Inoue, Minako; Shimamoto, Tetsuo; Shima, Keiyuu; et al. Journal of Medicinal Chemistry, 1988 , vol. 31, # 7 p. 1295 - 1305

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Citation Number: 32

Abstract

R,= H, OCH,. OH X= Cl, Br (1); 9-methoxyellipticine (2); and 9-acetoxyellipticine (3) 6] with an equimolar amount of peracylated glycosyl halides (I) in aprotic polar solvents (eg, nitromethane, acetonitrile, etc.). 20 However, this method is not satisfactory due to low ...