Amides of n-acylcysteines as mucolytic agents

TA Martin, DH Causey, AL Sheffner…

Index: Martin,T.A. et al. Journal of Medicinal Chemistry, 1967 , vol. 10, p. 1172 - 1176

Full Text: HTML

Citation Number: 9

Abstract

Mucolytic Data.-The activity of three compounds in reducing the viscosity of a mucoproteinlz solution is shown in Table 11. XAC is included as reference material. Substantially greater mucolytic activity is demon5tr:~ ted by the 2-acylamino-3-mercaptopropiorl-amides (1-5) ut each time period. Two less soluble compounds (6 and 7) do not show good activity. Oxidative Stability.-In addition to the good mucolytic I) ropertics esliihitccl by severd of ...

Related Articles:

Synthetic analogs of the active sites of iron-sulfur proteins. VI. Spectral and redox characteristics of the tetranuclear clusters [Fe4S4 (SR) 4] 2

[DePamphilis,B.V. et al. Journal of the American Chemical Society, 1974 , vol. 96, p. 4159 - 4167]

Synthetic analogs of the active sites of iron-sulfur proteins. VI. Spectral and redox characteristics of the tetranuclear clusters [Fe4S4 (SR) 4] 2

[DePamphilis,B.V. et al. Journal of the American Chemical Society, 1974 , vol. 96, p. 4159 - 4167]

Synthetic analogs of the active sites of iron-sulfur proteins. VI. Spectral and redox characteristics of the tetranuclear clusters [Fe4S4 (SR) 4] 2

[DePamphilis,B.V. et al. Journal of the American Chemical Society, 1974 , vol. 96, p. 4159 - 4167]

Studies on the reactivity of bicyclomycin with nucleophilic amino acid derivatives

[Abuzar, Syed; Kohn, Harold Journal of Organic Chemistry, 1989 , vol. 54, # 16 p. 4000 - 4003]

Facile trisulphide formation in the thermolysis of N, N′-diacetyl-L-cystine bismethylamide, an excellent model for protein-bound cystine

[Ghadimi, Moharam; Hill, Roger R. Journal of the Chemical Society, Chemical Communications, 1991 , # 13 p. 903 - 904]

More Articles...