Molecular properties of the adrenergic. alpha. receptor. 2. Optimum covalent inhibition by two different prototypes of polyamine disulfides

C Melchiorre, MS Yong, BG Benfey…

Index: Journal of Medicinal Chemistry, , vol. 21, p. 1126 - 1132

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Citation Number: 68

Abstract

... Concrete evidence that the chemical reactivity of the disulfide part of BHC is indeed responsible for receptor inactivation is found in the fact that the all-carbon analogue of BHC (38, Scheme 11) caused no inactivation under the same ... Journal of Medicinal Chemistry, 1978, Vol. ...