Synthesis, electrochemical, and spectroscopic studies of novel S-nitrosothiols

L Soulère, JC Sturm, LJ Núñez-Vergara, P Hoffmann…

Index: Soulere, Laurent; Sturm, Juan-Carlos; Nunez-Vergara, Luis J.; Hoffmann, Pascal; Perie, Jacques Tetrahedron, 2001 , vol. 57, # 33 p. 7173 - 7180

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Citation Number: 17

Abstract

A series of S-nitrosothiol compounds, structurally related to the NO-donor S-nitroso-N-acetyl- d, l-penicillamine (SNAP) that contain amidin groups were synthesised by S-nitrosation of the corresponding thiols and characterised. The kinetics of decomposition were investigated and showed that the two adenine-based thionitrites exhibited an unusual stability in aqueous solution compared to SNAP, suggesting that these compounds may complex the ...