Tetrahedron

Palladium-catalysed aminocarbonylation of iodoarenes and iodoalkenes with aminophosphonate as N-nucleophile

A Takacs, A Petz, L Kollar

Index: Takacs, Attila; Petz, Andrea; Kollar, Laszlo Tetrahedron, 2008 , vol. 64, # 37 p. 8726 - 8730

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Citation Number: 17

Abstract

The high-yielding synthesis of novel N-acyl phosphonates with unprecedented structure was carried out by a homogeneous carbonylation reaction under mild reaction conditions. The palladium-catalysed aminocarbonylation of iodoalkenes (1-iodo-cyclohexene, 1-iodo-4-tert- butyl-cyclohexene, 1-iodo-2-methyl-cyclohexene and α-iodostyrene) with diethyl α- aminobenzyl-phosphonate as N-nucleophile resulted in the exclusive formation of ...