Synthesis of 7-oxa-phomopsolide E and its C-4 epimer
M Li, J Scott, GA O'Doherty
Index: Li, Miaosheng; Scott, Jana; O'Doherty, George A. Tetrahedron Letters, 2004 , vol. 45, # 5 p. 1005 - 1009
Full Text: HTML
Citation Number: 64
Abstract
A flexible, enantioselective route to highly functionalized α, β-unsaturated δ-lactones has been applied to the synthesis of 7-oxa-phomopsolide E and its C-4 epimer. This approach relies on the application of the Noyori asymmetric hydrogenation of furyl ketone to produce the secondary furyl alcohol in high enantioexcess, which can be stereoselectively transformed into α, β-unsaturated-δ-lactones by a short, highly diastereoselective ...
Related Articles:
[Rui, Fabio; Marques, Joao C.; Miller, Stephen T.; Maycock, Christopher D.; Xavier, Karina B.; Ventura, M. Rita Bioorganic and Medicinal Chemistry, 2012 , vol. 20, # 1 p. 249 - 256]
[Cheng, Zhenzhuang; Hamada, Yasumasa; Shioiri, Takayuki Synlett, 1997 , vol. 1997, # 1 p. 109 - 110]
[Wipf, Peter; Wenjing, Xu; Hongyong, Kim; Takahashi, Hidenori Tetrahedron, 1997 , vol. 53, # 48 p. 16575 - 16596]
[Wipf, Peter; Wenjing, Xu; Hongyong, Kim; Takahashi, Hidenori Tetrahedron, 1997 , vol. 53, # 48 p. 16575 - 16596]
[Wipf, Peter; Wenjing, Xu; Hongyong, Kim; Takahashi, Hidenori Tetrahedron, 1997 , vol. 53, # 48 p. 16575 - 16596]