The Preparation of Some Analogues of Myristoyl CoA

…, AS Gopalan, R Raghavachari, LJ Guziec…

Index: Pankayatselvan, Ratna; Guziec, Frank S.; Gopalan, Aravamudan; Raghavachari, Ramesh; Guziec, Lynn James; et le. Organic Preparations and Procedures International, 1995 , vol. 27, # 3 p. 347 - 354

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Abstract

Acylation of cellular and viral proteins by fatty acids has recently been recognized as an important post-translational protein modification. In some cases such protein acylation may be neces-sary for viral replication and retroviral induced events such as tumorigenesis and immunosuppression. N-Myristoylation of the N-terminal glycine of various cellular, oncogenic and viral proteins appears to be a particularly important modification and is the ...