Total Synthesis of (-)-Furaquinocin C

AB Smith III, JP Sestelo, PG Dormer

Index: Smith III, Amos B.; Sestelo, Jose Perez; Dormer, Peter G. Journal of the American Chemical Society, 1995 , vol. 117, # 43 p. 10755 - 10756

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Citation Number: 26

Abstract

The furaquinocins (AH, 1-8), isolated by 6mura and coworkers' at the Kitasato Institute (Tokyo) from the fermentation broth of Streptomyces sp. KO-3988, manifest wide-ranging biological effects, including in vitro cytotoxicity against HeLaS3 cells, 2 antihypertensive activity, and inhibition of platelet aggregation and c~ agulation.~ In 1992, as a prelude to total