Journal of the American Chemical Society

Conformational analysis of protected norvaline oligopeptides by high resolution proton magnetic resonance

ES Pysh, C Toniolo

Index: Pysh,E.S.; Toniolo,C. Journal of the American Chemical Society, 1977 , vol. 99, p. 6211 - 6219

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Citation Number: 41

Abstract

Abstract: Proton magnetic resonance spectra at 270 MHz are reported for Boc (L-Nva),, OMe, n= 1-4. and for Ac-l.-Nva-OMc. in CDCI, and CDC13IMe2SO-dh mixtures. A method is reported for assigning theC" H resonance at theC-terminal rcsidue of ester C-protected peptides, based on the downfield shift of that resonance in CDCIj with increasing temperature. No rolded forms are found for the unaggregated dipeptide (0.009 M), but ...